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Hyaluronic
Acid Knowledge |
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Sodium Hyaluron-ate Gel |
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What is Hyaluronic Acid? |
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The Dangers of Hyaluronic Acid |
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Does Hyaluronic Acid Really
Work? |
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The Multi-Faceted Benefits of
Hyaluronic Acid |
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Steroid and Hyaluronic Acid
Injections for Osteoarthritis Pain |
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Sodium Hyaluron-ate Gel |
Sodium Hyaluron-ate Gel is used
for:
Treating dry, scaly skin.
Sodium hyaluronate:cosmetics
grade,food grade,eye drop grade,injection
grade,feedstuff grade Gel is a mucopolysaccharide. It works
by replacing a substance found in the skin.
Do NOT use Sodium Hyaluron-ate
Gel if:
you are allergic to any ingredient in Sodium Hyaluronate:cosmetics,food,eye
drop,injection,feedstuff£¬
Gel
Contact your doctor or health care provider right away
if any of these apply to you.
Before using Sodium
Hyaluron-ate Gel:
Some medical conditions may interact with Sodium
hyaluronate Gel. Tell your doctor or pharmacist if you
have any medical conditions, especially if any of the
following apply to you:
¡öif you are
pregnant, planning to become pregnant, or are
breast-feeding
¡öif you are
taking any prescription or nonprescription medicine,
herbal preparation, or dietary supplement
¡öif you have
allergies to medicines, foods, or other substances
Some MEDICINES MAY INTERACT with
Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade Gel.
Because little, if any, of Sodium Hyaluron-ate Gel is
absorbed into the blood, the risk of it interacting with
another medicine is low.
This may not be a complete list of all interactions that
may occur. Ask your health care provider if Sodium
Hyaluron-ate Gel may interact with other medicines that
you take. Check with your health care provider before
you start, stop, or change the dose of any medicine.
How to use Sodium Hyaluron-ate
Gel:
Use Sodium Hyaluron-ate Gel as directed by your doctor.
Check the label on the medicine for exact dosing
instructions.
¡öWash your
hands before and after using Sodium Hyaluronate Gel,
unless your hands are part of the treated area.
¡öApply a
generous amount of medicine to the affected area and rub
in well.
¡öIf you miss a
dose of
Sodium hyaluronate:cosmetics
grade,food grade,eye drop grade,injection
grade,feedstuff grade Gel, use it as soon as
possible. If it is almost time for your next dose, skip
the missed dose and go back to your regular dosing
schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have
about how to use Sodium Hyaluron-ate Gel.
Important safety information:
¡öSodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade Gel is for external use only. Do not get
Sodium Hyaluron-ate Gel in your eyes, nose, or mouth. If
you get Sodium
hyaluronate:cosmetics grade,food grade,eye drop
grade,injection grade,feedstuff grade Gel in your eyes, rinse with
cool water right away.
¡öDo not use
Sodium Hyaluron-ate Gel for other skin conditions at a
later time.
¡öPREGNANCY and
BREAST-FEEDING: It is unknown if Sodium Hyaluronate Gel
can cause harm to the fetus. If you become pregnant
while taking Sodium Hyaluron-ate Gel, discuss with your
doctor the benefits and risks of using Sodium
Hyaluronate :cosmetics,food,eye drop,injection,feedstuff, Gel during pregnancy. It is unknown if
Sodium Hyaluron-ate Gel is excreted in breast milk. If
you are or will be breast-feeding while you are using
Sodium Hyaluron-ate Gel, check with your doctor to
discuss the risks to your baby.
Possible side effects of Sodium
Hyaluron-ate Gel:
All medicines may cause side effects, but many people
have no, or minor, side effects. No COMMON side effects
have been reported with Sodium Hyaluronate
cosmetics,food,eye drop,injection,feedstuff, Gel. Seek
medical attention right away if any of these SEVERE side
effects occur:
Severe allergic reactions (rash; hives; difficulty
breathing; tightness in the chest; swelling of the
mouth, face, lips, or tongue).
Proper storage of Sodium
Hyaluron-ate Gel:
Store Sodium
hyaluronate:cosmetics grade,food grade,eye drop
grade,injection grade,feedstuff grade,Gel at room temperature,
between 59 and 86 degrees F (15 and 30 degrees C). Store
away from heat, moisture, and light. Keep Sodium Hyaluronate Gel out of the reach of children and away
from pets.
General information:
¡öIf you have
any questions about Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade Gel, please talk
with your doctor, pharmacist, or other health care
provider.
¡öSodium
Hyaluronate(Hyaluronic Acid(HA,Hyaluronan) ) Gel is to be used only by the patient for
whom it is prescribed. Do not share it with other
people.
¡öIf your
symptoms do not improve or if they become worse, check
with your doctor.
This information is a summary only. It does not contain
all information about Sodium Hyaluronate Gel. If you
have questions about the medicine you are taking or
would like more information, check with your doctor,
pharmacist, or other health care provider |
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Article Source: |
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http://www.drugs.com/cdi/sodium-hyaluron-ate-gel.html |
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Steroid and Hyaluronic Acid
Injections for Osteoarthritis Pain |
Experts agree that the best treatment for osteoarthritis
is a combination of education, lifestyle changes such as
losing weight and exercising, and medication. But when
the usual lifestyle strategies and pain relieving
medications are not doing enough, or when side effects
keep you from taking your meds, your doctor may
recommend injecting medicine directly into an
osteoarthritic joint.
Osteoarthritis Treatment: Steroid Injecti-ons
The medications that can be used via injection for
osteoarthritis treatment are corticosteroids and hyaluronic acid
(HA,Hyaluronan). "Steroid and hyaluronic acid injections(Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade) are both safe, temporary measures that provide pain
relief," says Jason Koh, MD, an orthopedic surgeon at
Northwestern Memorial Hospital in Chicago.
Your doctor will first numb the joint area, then put a
long needle into the joint space. If there is too much
fluid inside the joint, it will first be removed and
then the medication will be injected into the joint.
These procedures can be done right in your doctor's
office and you can go home afterward. Your doctor will
provide post-procedure instructions but for most people
the recovery period is not difficult.
Corticosteroids are synthetic drugs that block
inflammation by acting like hormones in your body. Since
joint inflammation is a major cause of osteoarthritis
pain, steroid injecti-ons can help for a while. The pain
relief is immediate but temporary, and will gradually
wear off as you begin using the joint again.
Osteoarthritis treatment with steroid injections is
usually done on knee or hip joints. Inject-ions into the
hip joint are harder to do, and the evidence that this
osteoarthritis treatment works for the hip is not as
strong as it is for the knee.
"Multiple steroid injections may weaken joint tissue, so
I typically recommend no more than two to three a year,
maximum. Patients have variable responses: Some get no
relief; others get up to six months," notes Dr. Koh.
There is also an increased chance of getting an
infection in the joint after steroid osteoarthritis
treatment.
Steroid inject-ions are relatively inexpensive and are
covered by most insurance plans.
Osteoarthritis Treatment: Hyaluronic Acid Injection£¨Sodium
hyaluronate:cosmetics grade,food grade,eye drop
grade,injection grade,feedstuff grade£©
Hyaluronan, Koh says, is an artificial form of the
body's own lubricating fluid for joints: ¡°There is
little risk, but three to five shots are usually
required.¡± The treatment¡¯s effects usually last three to
six months, he says, with about 75 to 85 percent of
people experiencing significant pain relief. ¡°These can
be repeated without bad effects,¡± he says, noting that
Hyaluronan treatments are more expensive than
steroids, but are covered by most insurance plans and
Medicare if certain criteria are met.
Hyaluronan was first approved by the Food and Drug
Administration for osteoarthritis treatment in 1997. A
recent review of 76 clinical trials that studied hyaluronic acid (HA,Hyaluronan) inject-ions(Sodium
hyaluronate:cosmetics grade,food grade,eye drop
grade,injection grade,feedstuff gradef)as an osteoarthritis
treatment concluded that hyaluronic acid worked to
relieve osteoarthritis pain as well as oral pain
medications, and that the results lasted longer than
steroid inject-ions for osteoarthritis treatment.
If you are still having pain despite lifestyle changes
and oral medical treatment, or if you can't take oral
medication because of side effects, speak to your doctor
about using joint inject-ions. These osteoarthritis
treatments are not a cure for the disease, but they can
effectively get you through a flare-up of your
osteoarthritis pain in a relatively safe manner. |
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Article Source: |
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http://www.everydayhealth.com/osteoarthritis/injections-for-arthritis-pain.aspx |
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The Dangers of Hyaluronic Acid |
Touted by beauty experts and the media as the "fountain of
youth" (one of a plethora of anti-aging miracle
ingredients marketed to the public), Hyaluronan is a naturally occurring "goo" produced in the body
and distributed through connective, epithelial, and
neural tissues. It acts primarily as a lubricant and
cushion to protect cells. H-A(Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade) has been synthesized in
laboratories and used as a main ingredient in anti-aging
cosmetic products as an inject-ion or topical
application. Also called Hyaluronan, this gooey
substance is abundantly produced and distributed
throughout the body, especially in areas where there is
a connective tissue disorder.
Allergies
Hyaluronic Acid(HA,Hyaluronan) gel is sometimes injected in certain parts of the
body (such as the lips, cheeks or thighs) to prevent
those parts from aging. The inject-ions, which are
supposed to be safe and nonallergenic, are administered
by a medical expert, usually in a beauty and wellness
clinic. For some people, particularly those with a low
threshold for pain and those who have sensitive skin,
these inject-ions can be painful and lead to redness,
swelling or inflammation of the skin. Other known side
effects include acne and necrosis (the premature death
of cells or tissues).
Reported Side Effects
Some of the side effects reported by patients who have
had hyaluronic knee inject-ions for treating
Hyaluronic Acid(HA,Hyaluronan) (Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade)
abnormalities include coughing, difficulty swallowing,
dizziness, nausea, fever, itching, nasal congestion, and
skin rashes. Some have reported pain, bruising, or
swelling in the area of inject-ion while others have
encountered acute headaches, diarrhea, difficulty
breathing, loss of appetite and stomach ache.
Contraindications
Certain medications such as aspirin, NSAIDs
(non-steroidal inflammatory drugs such as ibuprofen and
paracetamol), St. John's Wort, and Vitamin E supplements
can increase swelling and bleeding after inject-ions of
Hyaluronic Acid(HA,Hyaluronan) . As a result, it is best to avoid these medications
for at least a week prior to the inject-ions. A good
doctor will forewarn the patient about these
contraindications and the possible side effects and
dangers of H-A.
HA Imbalance
Abnormal levels of Hyaluronic Acid(HA,Hyaluronan) can occur artificially or
naturally. Particularly susceptible are those with
connective tissue disorders (CTDs). As with any kind of
substance in the body such as hormones, proteins and
nutrients, too much or too little can lead to health
problems. Because of excess production, connective
tissue disorders can lead to H-A abnormalities that
trigger health complications. These complications
include mitral valve response, keratoconus, Marfan
syndrome, Ehlers-Danlos syndrome, stickler syndrome,
Osteogenesis imperfecta, and osteoarthritis. High levels
of
Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade have also been connected to some forms of cancer.
In general, healthy people have a healthy dose of Hyaluronic Acid(HA,Hyaluronan)
circulating in their bodies and hardly need
supplementation.
Symptomatic
H-A abnormality is usually indicative of a connective
tissue disorder and is a symptom rather than a primary
medical condition. When the main problem is treated,
such as osteoarthritis and muscle contractures, Hyaluronic Acid(HA,Hyaluronan)
production and distribution will most likely go back to
normal levels. |
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Article Source: |
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http://www.ehow.com/about_5347422_dangers-hyaluronic-acid.html |
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The Multi-Faceted Benefits of
Hyaluronic Acid |
Last month, we introduced a new highly bioavailable form
of Hyaluronan that provides the most effective
delivery system available for this nutrient. This month,
we will focus on the many ways that this high molecular
weight H-A£¨Sodium
hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade£© lozenge can contribute to overall health.
H-A is ubiquitous throughout the body, the highest
amounts being found in the extracellular matrix of soft
connective tissues such as synovial fluid (joint
lubricant), vitreous fluid in the eyes, and in the skin.
It is involved in several key processes, including cell
signaling, wound repair and regeneration, morphogenesis,
and matrix organization.1 As a fundamental component
that helps maintain cellular structure and function,
Hyaluronic Acid(HA,Hyaluronan)
acts as a lubricant, an antioxidant, a shock absorber
during weight bearing, and a cushion to protect against
physical trauma. The fact that H-A is so important in so
many aspects of health makes it particularly unfortunate
that the levels of Hyaluronic Acid(HA,Hyaluronan) decline with advancing age.
H-A supplementation can make up for age-related
deficiencies of this nutrient. Research has shown
success with Hyaluronic Acid(HA,Hyaluronan) supplementation in inflammatory
processes in areas such as rheumatology, ophthalmology,
dermatology, and dentistry, as described below.
Joint Protection
H-A has been used in osteoarthritis for more than 30
years. Many studies have documented the long-lasting
pain-relieving effects of intra-articular
supplementation with H-A in subjects with knee
osteoarthritis, a procedure that was approved by the FDA
in 1997.2
Oral supplementation with Hyaluronic
Acid(HA,Hyaluronan)(Sodium
hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade) also shows promising
results as seen in a recent study. This
placebo-controlled trial enrolled 20 male and female
subjects aged 40 years and older with knee
osteoarthritis (pain for at least 15 days in the
previous month and symptoms present for at least 6
months) who were randomized to oral supplementation of
Hyaluronic Acid(HA,Hyaluronan) or placebo.3 At the end of the study period,
H-A-treated participants experienced a greater decrease
in total symptom scores based on a standardized
osteoarthritis index, compared with placebo after just 8
weeks (-18.6 vs -15.8). There was also a greater
magnitude of pain relief in the H-A-treated group
compared with placebo (11.1 vs. 2.2) as well as a
significant improvement in physical component summary
scores (6.1 vs. 3.6). The researchers also observed that
the Hyaluronic Acid(HA,Hyaluronan) group needed half the amount of pain rescue
medication (500 mg acetaminophen capsules) compared with
the placebo group during the study. In addition,
compared with placebo, more H-A subjects perceived
improvement in joint pain (75 percent vs. 50 percent)
and muscle aches (75 percent vs. 38 percent). The
researchers concluded that oral HA ¡°was useful to
enhance several markers of quality of life in adults
with osteoarthritis of the knee.¡±
The impressive results seen with oral H-A(Sodium
hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade) supplementation
may be particularly advantageous in elderly subjects in
whom osteoarthritis-related pain results in a serious
limitation of activities of daily living.3 Oral
supplementation also has obvious advantages over intra-articular
Hyaluronic Acid(HA,Hyaluronan) by avoiding potential complications at the injection
site and discomfort associated with repeated
inject-ions.4
Clinical studies have confirmed anti-inflammatory,
anabolic, and cartilage-protective actions of HA in
reducing pain and improving patient function.5
Hyaluronic Acid(HA,Hyaluronan)
appears to have a stimulatory effect on the metabolism
of chondrocytes (cells found in the cartilage) through
its interaction with CD44 receptors.6
Researchers have speculated this could lead to permanent
improvement of cartilage with oral supplementation,
which can elevate plasma Hyaluronic
Acid(HA,Hyaluronan) concentrations over a long
time period.3
A growing body of evidence also indicates that
mitochondrial dysfunction and DNA damage play a causal
role in disorders such as osteoarthritis that are linked
to excessive generation of free radicals. Pretreatment
of chondrocytes with Hyaluronic Acid(HA,Hyaluronan) has been shown to enhance their
survival by decreasing mitochondrial damage and
enhancing DNA repair capacity and cell viability, while
preserving ATP levels and ameliorating apoptosis.7
Furthermore, studies have shown that the concentration
and level ofHyaluronic Acid(HA,Hyaluronan)(Sodium
hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade) decline significantly in inflammatory
arthritis,8 which can be counteracted with high
molecular weight H-A supplementation. This measure has
proved effective in promoting chondrocyte Hyaluronic
Acid (HA,Hyaluronan) and proteoglycan synthesis, reducing the production of
substances that break down collagen such as
proinflammatory mediators and enzymes called matrix
metalloproteinases (MMPs), and maintaining joints in
good condition.8
Temporomandibular Joint (TMJ)
Syndrome
As with osteoarthritis, the level of Hyaluronic
Acid(HA,Hyaluronan) is significantly
lower in the synovial fluid from patients with
inflammation of the temporomandibular joint, which
connects the jaw to the skull.9 Hyaluronan has a
natural affinity for joint tissue. In one study, the
intra-articular administration of sodium hyaluron-ate
into the temporomandibular joint in patients with Wilkes
stage II disease (a classification used to define TMJ
severity according to 5 stages) showed better efficacy
in reducing pain and improving joint function compared
with the oral administration of pain-relief tablets.10
Promoting Healthy Skin
In 2003, the FDA approved hyaluronic acid injections £¨Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade£© for
filling soft tissue defects such as facial wrinkles.
Hyaluronic Acid (HA,Hyaluronan)
and collagen are both vital components of skin tissue.
However, there is a progressive reduction in the number
of hyaluro-nic acid granules in human skin, deteriorating
to a complete absence in individuals over 60. It is
believed these variations account for the decreased
turgidity, wrinkled appearance, and altered elasticity
of skin tissue.11 The regulation of major skin cells
known as fibroblasts is central to both healing and
scarring processes. Laboratory studies show that
supplementing fibroblasts with Hyaluronic
Acid(HA,Hyaluronan)£¨Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade£© causes a significant
increase in their ability to renew skin tissue,
resulting in increased proliferation within the collagen
matrix.12
The anti-inflammatory effects of H-A also carry important
implications for collagen regeneration in maintaining
healthy skin. The cutaneous benefits of H-A can be seen
in studies where it has been shown to block IL-1b, a
cytokine that inhibits collagen biosynthesis at the
transcriptional level.13 IL-1 also inhibits the
expression of insulin-like growth factor-1, a highly
potent stimulator of collagen synthesis, while
Hyaluronic Acid(HA,Hyaluronan)
counteracts this process.14 H-A also suppresses MMP-1,
which preferentially breaks down major components of
collagen in the skin,15 and reduces levels of an
inflammatory chemokine called RANTES. Both processes are
mediated partly by the interaction of H-A(Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade) with its
receptor called CD4416 that is found in abundance in the
oral mucosa, making the use of an Hyaluronic
Acid(HA,Hyaluronan) lozenge
particularly useful for maintaining healthy skin..
The effectiveness of H-A also extends to skin disorders
such as oral lichen planus (OLP), a common inflammatory
disease of the skin and mouth. In a study of 124
patients with oral lichen planus, HA significantly
reduced soreness scores compared with placebo for up to
4 hours.17 Patients treated for up to 28 days with
Hyaluronic Acid (HA,Hyaluronan)
showed a significant reduction in the size of the
erosive/ulcerated area compared with baseline. The
researchers concluded that HA may be a ¡°useful addition
to the treatment option for OLP.¡±
In the above study, Hyaluronic Acid(HA,Hyaluronan£¬Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade) was used in direct contact with
the mucus membranes. A 30 mg lozenge provides an ideal
delivery system for this type of use since it delivers
more H-A for equal or longer periods of time to target
tissues.
Managing Ocular Health
Another important body system where Hyaluronic Acid (HA,Hyaluronan) distribution
declines dramatically with aging is in human eye
tissue.18 Researchers have speculated that this decline
may play a role in age-related ocular disorders.18
UV light is the most common cause of radiation injury to
the eye. While the cornea absorbs most UVB light to
protect the inner eye, exceeded threshold levels induce
corneal inflammation (photokeratitis). UVB light also
triggers different signaling cascades that cause
apoptosis of corneal cells. However, researchers have
recently shown for the first time that high molecular
weight H-A protects human corneal epithelial cells
against UVB-induced apoptosis as well as decreasing UVB-induced
release of the proinflammatory mediators IL-6 and
IL-8.19 Corneal cells express CD44 receptors on their
plasmic membranes, which is a specific point of
interaction for Hyaluronic Acid(HA,Hyaluronan). It is believed that this may be a
key factor in understanding how H-A protects against UVB
radiation.19 H-A£¨Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade£© supplementation can also be useful to
people with dry eyes as well as people suffering eye
discomfort after computer use.20-22
Maintaining a Healthy Oral
Cavity
Another emerging benefit for the use of Hyaluronic
Acid(HA,Hyaluronan) is in the
treatment of plaque-induced gingivitis. H-A has shown
anti-inflammatory and antibacterial effects in both
gingivitis and periodontitis. It is important to
remember that oral disease processes contribute to
cardiovascular disease and total inflammatory burden in
the body, including elevated C-reactive protein, and the
condition of the mouth and gums is therefore important
to overall health. Due to its tissue-healing properties,
H-A may be a useful adjunct in diseases of the oral
cavity.23-24 The availability of Hyaluronic
Acid(HA,Hyaluronan£¬Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade) in a lozenge
preparation, which is well absorbed across the oral
mucosa, enhances its effectiveness for optimizing dental
hygiene.
H-A has also been shown to be of benefit in recurrent aphthous ulcers, or canker sores, which are painful open
sores inside the mouth or upper throat caused by breaks
in the mucous membrane.25 In addition, in vivo studies
show that sodium hyaluron-ate effectively accelerates the
healing process after tooth extraction by stimulating
the expression of bone-forming proteins.26
Another oral condition that may cause difficulties in
speech and eating as well as increasing the
susceptibility of periodontal tissue to infection is
known as xerostomia, or dry mouth, which is a common
complaint in the elderly. Elderly patients with dry
mouth, not caused by any history of connective tissue
disease, have been shown to have lower Hyaluronic
Acid(HA,Hyaluronan) levels in
their saliva compared with age-matched controls.27 Oral
use of Hyaluronan improved hyposalivation and
unpleasant oral complaints associated with dry mouth.28
Conclusion
H-A is a vital component of cellular structure and offers
a multitude of benefits including anti-inflammatory and
antioxidant effects, pain-relief, joint lubrication and
cartilage-protection, collagen regeneration, and
enhancement of cell viability. Most of these actions are
mediated via the H-A-specific CD44 receptor present on
endothelial, epithelial, and smooth muscle cell
membranes. Since H-A declines naturally with age, oral H-A£¨Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade£©
supplementation with a new lozenge offers an efficient
alternative, which is well absorbed through the highly vascularized oral mucosa that is rich in CD44 receptors.
As a result, oral HA supplementation offers an effective
solution for joint protection, maintaining healthy skin
and eyes, and is a useful adjunct for good dental
hygiene. |
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Article Source: |
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http://www.vrp.com/articles.aspx?ProdID=2704 |
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What is Hyaluronic Acid? |
Hyaluronan is a type of polysaccharide called a glycosaminoglycan. Also known as hyaluronan or
hyaluron-ate, Hyaluronan occurs naturally in the
human body and is central to regulating cell growth and
renewal. In fact, it is found extensively in connective,
epithelial, and neural cells. As such, Hyaluronan
has found its way into many skin care products,
particularly anti-wrinkle formulations. In addition, it
has been credited with extending life in those who
consume copious amounts in the diet, resulting in the
media dubbing Hyaluronan as the ¡®key to the
fountain of youth.¡¯
The fact that this acid binds with water accounts for
the special interest in this substance in dermatology.
When injected under the skin, it provides an appearance
of fullness at the site, smoothing out fine lines and
wrinkles for up to six months. Administration of this
cosmetic procedure is available in the form of Restylane®,
a non-animal stabilized source of
Sodium hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade that is produced from bacteria. In addition to being a
corrective procedure for moderate to heavy wrinkling of
facial skin, it is a popular lip augmentation treatment.
As a skin care procedure, hyaluronic acid injections (Sodium
hyaluronate:cosmetics grade,food grade,eye drop
grade,injection grade,feedstuff grade)
present certain side effects for some individuals.
Temporary bruising, swelling, and redness at the
inject-ion site are fairly common. However, subjects
undergoing therapy with nonsteroidal anti-inflammatory
drugs, or who supplement with vitamin E or St. John¡¯s
Wort, are advised to stop taking these medications at
least one week prior to receiving these acid inject-ions
because of an increased risk of bleeding.
Ironically, while this acid may be touted as a beauty
enhancer, it can also diminish the appearance of skin
and even cause tissue damage. This is because Hyaluronan readily degrades in the presence of at least seven
enzymes classified as hyaluronidases. Degradation of
hyaluronan is significantly accelerated when the skin is
exposed to high levels of ultraviolet rays (UVs) from
the sun. As a result, both the acid and its by-products
are sometimes responsible for promoting inflammatory
response and even tumor cell proliferation. In fact,
hyaluronan levels are sometimes used as a biomarker for
prostate and breast cancers. However, since
Hyaluronic Acid(HA,Hyaluronan) plays a key role in tissue repair, it has solid
application in several medical treatments. For instance,
it has been used extensively to speed healing after
ophthalmic procedures, such as corneal transplantation,
and surgery to correct retinal detachment and glaucoma. Hyaluronic acid injection therapy is also used as a
treatment for osteoarthritis of the knee, ankle, and
shoulder. |
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Article Source: |
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http://www.wisegeek.com/what-is-hyaluronic-acid.htm |
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Does Hyaluronic Acid Really
Work? |
What is Hyaluro-nic Acid?
In healthy young skin, as that which is seen in babies
and young children, Hyaluronic Acid(HA,Hyaluronan) is found in
abundance. A naturally occurring substance made by the
body, Hyaluronan is also known as glycosaminoglycan (GAG) and can be found throughout the
connective tissue of the body. As the years go by and
the human body begins to age, the production of HA
begins to decrease. Individuals who smoke or otherwise
have an unhealthy lifestyle may see the effects of lower
H-A levels more quickly than those who maintain an active
and healthy diet and lifestyle.
Can Hyaluronic Acid Supplementation fight
wrinkles?
The result of declining Hyaluronic Acid(HA,Hyaluronan) levels initiates a
simultaneous reduction in the amount of water that can
be held by the cells of the connective tissue. When the
connective tissue becomes dehydrate several problems
begin to occur. First, wrinkles and fine lines make
their appearance on the surface of the skin. Second, the
skin begins to take on a brittle, dry look. And, third,
the occurrence of cellulite increases as the connective
tissue weakens and is no longer able to hold the
cellulite of the female body in its place. The cellulite
bubbles up to the surface of the skin and the familiar
bumps, lumps and cottage cheese looking skin appears.
Some studies show that
Sodium hyaluronate:cosmetics grade,food grade,eye drop grade,injection grade,feedstuff grade taken as a supplement cannot
be absorbed by the body. Other studies declare injecti-ons of H-A as the most efficient means to deliver
additional H-A to connective tissue. Topical applications
of H-A, as in the case of moisturizers, are a popular
method of adding HA to the skin surface. Topical use of
H-A tends to hydrate the top layer of skin, the
epidermis, resulting in smoother, softer skin, by
trapping moisture below the surface.
Hyaluronic Acid Alternatives
An alternative option to increase Hyaluronic
Acid(HA,Hyaluronan) levels in the body
is to supplement with an H-A precursor. Glucosamine is
needed to make H-A and can be added to the diet as a
routine supplement as a capsule, powder or tablet. The
cascade of steps when glucosamine is added to the diet
is an increase in the body¡¯s production of HA(Sodium
hyaluronate:cosmetics grade,food grade,eye
drop grade,injection grade,feedstuff grade), an
increase in water content inside the connective tissue
and surrounding areas, and an overall decrease in
wrinkles, lines and cellulite.
As a side note, almost 90% of glucosamine is absorbed by
the intestines making supplements an easy method to
increase the substance in the body. Additionally,
glucosamine supplements leading to increased Hyaluro-nic
acid production in the body are now being used quite
regularly for patients suffering from osteoarthritis. |
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Article Source: |
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http://www.stopcellulitewrinkles.com/hyaluronic_acid.htm |
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