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Hyaluronic Acid (HA)

Sodium Hyaluronate-Cosmetics grade

Sodium hyaluronate-Food grade

Sodium hyaluronate-Eye drop grade

Sodium hyaluronate-Injection grade

Sodium hyaluronate-Feedstuff grade

 
Hyaluronic Acid Knowledge 

Hylaform® Hyaluronic Acid Gel
Hyaluro-nic acid in the skin
Hyaluronic Acid (HA,Hyaluronan,sodium hyaluronate) Therapy
Hyaluronic Acid Supplements
sodium hyaluronate
Hyaluronan a Must in Eye Creams
 
 
Hylaform® Hyaluronic Acid Gel
Hylaform® is a clear, colorless gel synthesized from Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid), a naturally occurring substance found in the human body and integral to keeping tissue lubricated. Deficiencies in Hyaluronic Acid (Feedstuff grade) have been linked to osteoarthritis, TMJ, and other degenerative diseases. Hylaform® and Hylaform® Plus injections replace collagen and HA that have deteriorated over time to remove wrinkles, filling in the empty space while moisturizing and lubricating the surrounding tissue.

Benefits and Possible Dangers of Hyaluronic Acid
As Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid)is a naturally occurring chemical already present in skin, there is little chance of an allergic reaction or the body rejecting the injection. As a result, one of the benefits of Hyaluronic Acid (Feedstuff grade)  treatments is that no skin test is required to determine the patient's reaction, as with collagen; the treatment can simply be administered when the patient desires. Hylaform® injections immediately remove wrinkles, and the results last for many months. Unlike artificial substances, Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is not only natural but known for its health-promoting qualities; ABC News documented a village in Japan whose residents lived particularly long lives, which was at least in part attributed to diets rich in Hyaluronic Acid (Feedstuff grade).

There are potential dangers of certain HA treatments, however. Patients with avian allergies may not be eligible for Hylaform® or Hylaform® Plus, as the HA is harvested from rooster combs. There are potential reactions to the injection as well, including temporary discomfort, discoloration, and swelling. However, in general these reactions are less severe and pass more quickly than those from other injectable treatments.

What is Hylaform®?
Hylaform® is an FDA-approved injectable Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) gel produced by Inamed, a leading manufacturer of medical products. Hylaform® gel is a highly purified form of HA, very similar to that found naturally in the body, so no allergy tests are needed before receiving Hylaform® injections (though as mentioned previously, those with bird allergies should talk to their doctor before treatment). Similar to Restylane®, Hylaform® is injected just below the surface of the skin, where it draws in moisture and volume to reduce or remove the appearance of facial lines and wrinkles. The effects of Hylaform® injections last for about six months to nine months, at which point further treatment will be needed or the effects will diminish.

Hylaform® and Hylaform® Plus
Hylaform® and Hylaform® Plus are both derived from the same material and designed for the same purpose, though for different applications. Hylaform® is injected into finer lines and wrinkles to smooth out the skin and hydrate and lubricate the tissue beneath the surface. Hylaform® Plus is more concentrated and while it achieves the same lubrication and hydration, it is intended for deeper lines and creases in the face. Your doctor will determine which treatment is best for your individual situation and desired results.
Article Source:
http://www.docshop.com/education/dermatology/injectables/hylaform/

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Hyaluro-nic acid in the skin
Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) plays an important role in the way your skin looks, feels, and functions. A natural complex sugar found in all mammals, it's a major component of the connective tissue matrix in the dermis!the dense, inner layer of skin beneath the epidermis. This matrix is made up of Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) as well as two connective fibers!collagen and elastin.

By its nature, HA retains water like a sponge, absorbing more than 1,000 times its weight. This helps to attract and maintain water within the extra-cellular space, hydrating your skin and increasing its volume and density. Hyaluro-nic acid is also involved with the transport of essential nutrients to the skin's viable cells. Hyaluronic Acid (Feedstuff grade)  provides volume, helping to contribute to the skin's overall appearance.

As you age and your skin is exposed to environmental pollutants and the sun's ultraviolet rays, your cells gradually lose the ability to produce hyaluro-nic acid. Studies have shown that older skin typically has lower levels of HA than younger skin. As you age, your skin tissue becomes dehydrated and the collagen and elastin fibers lose their structure, resulting in a loss of skin volume and the formation of the facial wrinkles and folds that are common characteristics of aged skin.

Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) plays many important roles within human skin including:
HA attracts water molecules and in this way maintains volume within the skin and helps prevent a dehydrated, wrinkled appearance of the skin. This is why the use of topical hyaluro-nic acid such as in Cellex-C Hydra 5 B-Complex and Cellex-C Skin Hydration Complex is so popular. But non-stabilized, hyaluro-nic acid only lasts a day or two. Restylane, which has 1% of the HA molecule stabilized is able to last for several months within the skin.
Hyaluro-nic acid has elastic properties that provide snap to the skin and prevent compression.
Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) gel inhibits the movement of bacteria and other foreign substances yet allows collagen fibers to move easily throughout the area.
Just like collagen and elastin fibers, the levels of hyaluro-nic acid diminish with the natural aging process.

Article Source:
http://www.hyaluronicacidserum.com/aboutha.htm

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Hyaluronic Acid  Therapy
Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) therapy is an increasingly popular cosmetic anti-aging solution. It involves the use of dermal fillers as a way of reducing the appearance of wrinkles and lending a more youthful appearance to the skin by "plumping" it up. Performed by dermatologists and plastic surgeons, HA therapy, like botox procedures, involves the injection of a hyaluronic-based dermal filler into the target skin areas. The non-surgical therapy uses popular hyaluronic filler brands like Restylane and Juvederm.
Dermal Fillers
Dermal fillers are made of Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade) or collagen, both of which are natural skin components. The filler is in the form of a clear gel that is injected into the skin, adding volume and lending a "plumping" effect from the inside out. This function is what makes textural irregularities of the skin, such as wrinkles, seem to vanish. Dermal fillers are also used to plump up the lips. Patients range widely in age from 30 to upwards of 60. The skin conditions of dermal filler patients also varies, though the filler is used as both a corrective and preventative anti-aging solution that is sometimes performed in conjunction with other cosmetic treatments.
Hyaluronic Acid
Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid)  exists in all living organisms and is found in high concentrations in the soft connective skin tissue. It is also found in the fluid surrounding the eye and in joint and cartilage fluids. The acid is a gel-like substance in the skin tissue that is spread between elastin and collagen fibers. It helps transport nutrients to the living skin cells from the bloodstream and helps keep the skin hydrated by retaining water. Hyaluronic Acid also acts as a lubricating balm against chemical and mechanical injury. As people age, the skin's supply of HA begins to degrade and deplete, a process that can be expedited by harmful environmental factors, like the sun.
Treatable Conditions
A synthetic form of Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is used in dermal fillers to treat a variety of skin conditions, most of which fall under the category of wrinkles, and most of which are in the facial area. Injections are made to smooth out the contour of frown lines, deep smile and marionette lines (lines from the nostrils to the corners of the mouth), forehead wrinkles, vertical smoker's lines around the mouth, crow's feet in the eye area, cheek depressions, facial scars (including acne scars) and thinning, aging lips. The injections plump up the skin's contour, thereby correcting facial depressions and other textural irregularities.
The Procedure
Small amounts of the Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) filler, such as Juvederm or Restylane, fill small vials attached to fine needles. The doctor first wipes the cleansed face with an antiseptic and then injects the target area(s). The treatment is completed within 20 minutes to an hour, depending on how many areas are treated. Local anesthetic may be used to numb the area, depending on the depth of the condition. The patient experiences minimal discomfort. Treatment sessions are not usually priced per session, but per vial. Marionette lines, for example, typically each require a half-vial of the dermal filler.
Possible Side Effects
Side effects are minimal. After Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) therapy session, the treated skin area may be swollen, tender and red. This subsides after a few days. During and immediately after treatment, the patient may experience mild discomfort.

Allergic reactions to hyaluro-nic acid injections result in thick nodules that form beneath the skin in the treated area. These may last for months and should be examined by a physician.
Lasting Effects
To achieve the desired results, a patient may need more than one treatment. Dermal fillers do not and cannot provide permanent results, as the injected filler will eventually dissolve. The results of Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) therapy last anywhere from three to nine months, depending on the age of the patient and the patient's skin condition and health. Patients who use HA therapy on a continual basis generally receive injections two or three times per year.
Article Source:
http://www.ehow.com/about_5464950_hyaluronic-acid-therapy.html

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sodium hyaluronate
HA is a naturally-occurring polysaccharide containing alternating N-acetyl-D-glucosamine and D-glucuronic acid monosaccharide units linked with beta 1-4 bonds and the disaccharide units linked with beta 1-3 glycoside bonds. It is a straight-chained polymer with a molecular weight varying between 50,000 and 13,000,000 Da, depending on the source from which it is obtained and the methods of preparation and determination used. Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) belongs to the group of glycosaminoglycans which also includes compounds containing sulfate groups (chondroitins, keratans and the heparans). HA is a critical component of connective tissue and typically exists in a state of strong association with proteins and other glycosoaminoglycans such as heparin and chondroitin sulfate. It is one of the chief components of the extracellular matrix, contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors. HA is naturally present in the pericellular gels, in the fundamental substance of connective tissue and in vertebrate organisms, of which it is one of the chief components, in the synovial fluid of joints, in the vitreous humor, in the human umbilical cord tissues and in rooster combs.

Health benefits of hyaluronic acid
HA plays a vital role in many biological processes such as tissue hydration, proteoglycan organisation, cell differentiation, proliferation and angiogenesis. Hyaluro-nic acid plays a fundamental role in tissue repair processes, especially in
the first stages of the process of the formation of granulation tissue, by stabilizing the coagulation matrix and controlling its degradation, favoring the recruitment of inflammatory cells, such as polymorphonucleocytes and monocytes, of mesenchymal cells, such as fibroblasts and endothelial cells, and directing the subsequent migration of epithelial cells.
Administration of Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) by intraarticular injection has been shown to be effective in the treatment of osteoarthritis. Osteoarthritis is characterized by a progressive loss of the particular cartilage of synovial joints with concomitant bony changes, including sclerosis and osteophyte formation. This is due not only to the unique viscoelastic properties of hyaluro-nic acid but also to its potential pharmacological properties. In the healthy knee joint, Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is present both in the cartilage covering the ends of bone and in the synovial joint fluid. The HA of the synovium is produced primarily by the synoviocytes that line the intima layer of the synovium, and proteins and nutrients that are drawn from the lymphatic system. The synovial fluid is a liquid form of an extracellular matrix that maintains the synovium volume and hydrostatic pressure, provides chondrocytes in the avascular particular cartilage with a steady flow of nutrients, lubricates the cartilage surface, and cushions the synovial tissue from the deforming forces of movements.

Its natural occurrence in the body and its ability to retain water have lead to the development and use of hyaluro-nic acid for various other therapeutic applications, e.g., the use of hyaluro-nic acid as a vitreous humor substitute, the prevention or inhibition of adhesions following surgery, and the protection of wounds during healing. Hyaluronan is also now a common skin care ingredient. In skin tissue, HA helps transport of essential nutrients from the bloodstream to living skin cells, hydrates the skin by retaining water, and acts as a cushioning and lubricating agent against mechanical and chemical damage. Since 2003 the FDA has approved hyaluronan injections for filling soft tissue defects such as facial wrinkles. These products are analgous to collagen injections but have the advantages of longer lasting effects and decreased risk of allergic reaction.

Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) may also be used postoperatively to induce tissue healing, notably after cataract surgery. Current models of wound healing propose that larger polymers of hyaluro-nic acid appear in the early stages of healing to physically make room for white blood cells, which mediate the immune response. In some cancers, hyaluro-nic acid levels correlate well with malignancy and poor prognosis. Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is thus often used as a tumor marker for prostate and breast cancer. It may also be used to monitor the progression of the disease. HA is effective in decreasing the adverse effects of autoimmune disease where the disease is mediated by T cells.

Sources of hyaluronic acid
HA is widely distributed in animal tissues, present in high concentrations in synovial fluid and the vitreous body of the eye, and in connective tissues of rooster comb, umbilical cord, and dermis. HA is commercially available and is prepared from the intracellular matrices of animal connective tissue, such as rooster combs and bovine tissue sources, mammalian umbilical cords, and bacterial organisms such as streptococcus zoepidicus. Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is obtainable not only by extraction from cockscombs and umbilical cords, but also as purified products from the culture broth of streptococci. Examples of the microorganisms capable of producing hyaluro-nic acid may include Streptococcus pyogenes, Streptococcus equisimilis, Streptococcus equi, Streptococcus dysgalactiae, Streptococcus zooepidemicus and the like.
Article Source:
http://www.vitamins-supplements.org/carbohydrates/hyaluronic-acid.php

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Hyaluronan a Must in Eye Creams
HA is a time-tested ingredient in eye creams. If you are in the market to buy an eye cream, make sure you read about Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) and what it can do to help you rejuvenate your under-eye skin.
There are very few ingredients that people will consider as miracle ingredients. However, in the case of eye creams, there happens to be one that has been making waves and garnering a lot of press for it's qualities in reducing dark circles under the eyes and even treating eye wrinkles.

Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) is an ingredient your skin naturally makes. It is naturally found in several tissues of the body, such as skin, such as the cartilage, and finally, in the vitreous humour. This makes it a capable ingredient when you talk about biomedical cosmetics that focus on these exact tissues.
Article Source:
http://www.buzzle.com/articles/hyaluronic-acid-a-must-in-eye-creams.html

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Hyaluronic Acid Supplements
HA is also known as hyaluronan or hyaluronate. Described as the ?goo? molecule, it is an ever-present carbohydrate polymer that is made up of an extra-cellular matrix and is a major component that makes up the joint fluid called the synovial fluid. This acid is found naturally in many tissues of the body, such as the skin, cartilage and vitreous humor.

In recent years, researchers have found medical applications for hyaluro-nic acid and have developed Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade) supplements made from this acid.HA supplements have been hailed as the next generation anti-aging nutritional supplement. By taking this supplement, you can have healthier skin. It supplies your skin with more moisture, resulting in a more youthful appearance.

The intake of this supplement also helps you build stronger, healthier and more flexible joints. It works as a shock absorber, lubricating the joints, and also works as an antioxidant. The supplement also helps protect the synovial fluid in your joints. It is also helpful in building your joint collagen, and taking it with grape seed extract helps normalize the production of HA to help maintain healthier veins in your legs.

Taking Hyaluronic Acid (Feedstuff grade) (Feedstuff grade Hyaluronic Acid) supplements improves your eye tissues and the health of your overall visual system. It increases the hyaluro-nic acid in the eye, loosening up the scaffolding of collagen structure, providing a structure of the matrix of material between the light-receptor cells in the retina. A hyaluronic acid eye drop has also been developed to relieve eye discomfort. This type of eye drop has also been used to heal the cornea damaged by the use of contact lenses. However, a Hyaluronic Acid (Feedstuff grade) supplement that is taken orally cannot be used for the eyes.

Usually Hyaluronic Acid (Feedstuff grade) (Hyaluronic Acid Feedstuff grade,Feedstuff grade Hyaluronic Acid) supplements are taken by injection, but there are HA supplements that can now be taken orally, though reportedly injection is still more efficient. The stomach has a hard time digesting hyaluro-nic acid taken orally, but oral intake can be safer than injecting the supplement.
Article Source:
http://EzineArticles.com/?expert=Kristy_Annely

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