Sodium Hyaluronate Food grade|Sodium Hyaluronate for Food grade|Food grade Sodium Hyaluronate

The Downsides and Upsides of Hyaluro-nic Acid Topical

Injectable Hyaluro-nic Acid Derivative Supplementation

Rooster comb hyaluronate-protein,a non-covalently linked complex

Is it Safe to Use Topical Hyaluro-nic Acid Skin Care Products to Preserve Our Youth Naturally?

(Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate)

Hyaluronic Acid is a natural intrinsic substance of the skin. Additional out-source Hyaluro-nic Acid may act as a supplement to the intrinsic HA of the skin. Because the lower relative molecular weight can penetrate through the surface of the skin and accelerate the nutritional supply of the skin and the excretion, so that it can prevent the skin from ageing. That means that Hyaluronic Acidmay function as a cosmetic substance as well as a nutrient.

Oral HA can increase Hyaluro-nic Acid content in human body, supply deficiency of Hyaluronic Acid. By digesting and absorbing HA, skin can be made moist, smooth, soft and rich spring. Oral Hyaluronic Acid can defer crowd senility; prevent arthritis, arteriosclerosis, plus disorder and brain atrophy. Oral Hyaluro-nic Acid can make one full of beans and be rich in youth energy.
HA has been widely applied in health and beauty food in America and Europe.

Technical standard:

Specification\Name	Sodium hyaluronate (Food grade)
Characters	White or straw yellow powder
Sodium Hyaluronate (dry basis)	90%-105%
Glucuronic acid	≥42.0%
PH(0.1% Water Solution)	6.0-8.0
Molecular Weight	(0.8-2.0)*10⁶
Protein	≤ 0.1%
Transparency (0.1% Solution)	≥99%
Residue on Ignition	≤20
Loss on drying	≤10.0%
Heavy metals (as Pb)	≤ 20ppm
Arsenic	≤2ppm
Bacteria count	≤ 100CFU/g
Mold & Yeast	≤10CFU/g
Salmonella	Negative
Escherichia coli	Negative
Packing	According to the request of the customers
Storage	Stored in an airtight container at 2-8 ^oC
Validity	Two years

the Latest Beauty Buzz

If you’ve been following the latest skin care news you’ll have noticed there’s a new wonder ingredient on the market - hyaluronic acid(Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate). Used previously as an injectable treatment for lines and wrinkles in the form of dermal fillers like Restylane, hyaluro-nic acid is now available for topical application in a range of gels, serums and moisturisers.

These products claim to dramatically improve the appearance of the skin and by doing so pander to the desire many of us have to find youth in a bottle. But what is hyaluro-nic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）, how does it work, and how effective can simply rubbing it on the surface of your skin be?

A Prevalent Sugar
Hyaluro-nic acid is a complex sugar, known as a glycosaminoglycan, and is found throughout the body. It is particularly prevalent in connective tissue, the synovial fluid around joints, the eyes, the heart, the intervertebral spinal disks and the skin.

It transports nutrients to cells and removes toxins, it acts as a cushioning agent, it lubricates joints and, importantly for the skin care industry, it facilitates water retention in body tissue. In fact, hyaluro-nic acid can absorb more than one thousand times its weight in water.

In the Skin
Picture your dermis, that layer if inner tissue beneath the surface (or epidermis) of your skin, as a sponge. The solid parts of that sponge are the collagen and elastin fibres that form the supporting matrix of the skin, and the spaces within the sponge are where the skin’s gel-like hyaluro-nic acid sits. Obviously, if you can pack those spaces with more water-rich hyaluro-nic acid your skin will have a fuller, firmer, more youthful appearance.

Skin Aging
Over time, and through the effects of UV radiation and environmental pollutants, the ability of the skin to produce hyaluro-nic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）, at a high in adolescence and early adulthood, declines. As a result, the skin becomes dehydrated - there’s less of the water-retaining gel in our sponge example - and the collagen/elastin structure loses it’s integrity. The result? Thinning of the dermis, a loss of skin radiance, and the formation of lines and wrinkles.

Topical Effectiveness?
It’s no wonder, then, that the notion of replenishing the skin’s hyaluro-nic acid has become a popular focus for skin care companies and beauty enthusiasts alike. But can it be done by the topical application of hyaluro-nic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） gels and serums?

There are two areas those seeking more youthful-looking skin should consider:

1/ When used as a moisturiser for the surface of the skin (as opposed to dermal replenishment) it has been suggested that hyaluro-nic acid’s great affinity for water may, if it is used in high concentrations and in very dry climates, actually back-fire on the user by pulling moisture out of the skin - the exact opposite of what the product is intended to do.

2/ Much of the buzz around hyaluronic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） centres on its ability to rebuild the skin matrix - to plump out those spaces in our sponge. But can it actually penetrate that deeply? Hyaluro-nic acid molecules vary in size. As large molecules (those with a molecular weight over, say, 20,000 Daltons) cannot effectively penetrate the skin, a product that uses large molecule hyaluro-nic acid may be of limited value in replenishing dermal hyaluro-nic acid. In order for hyaluronic acid （Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）to penetrate the skin the molecule must be micronised, or chopped into fragments.

Youth in a Bottle
The prospect of transforming your skin, not just at its surface, but right down at its foundations, is a tantalising one. Who wouldn’t want smoother, more radiant, youthful-looking skin? But while the science of hyaluronic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） is sound - it’s a component of the skin matrix, it has a massive ability to hold moisture - its actual effectiveness as a topical application should be carefully researched by those seeking youth in a bottle, particularly as these skin care products are some of the more costly available.

Article Source:

http://howto.yellow.co.nz/fashion-and-beauty/appearance-enhancement/hyaluronic-acid-serums-and-moisturisers-%E2%80%93-the-latest-beauty-buzz/

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The Downsides and Upsides of Hyaluronic Acid Topical

What is hyaluronic acid?
Before you get into the advantages and disadvantages, you have to know first what hyaluro-nic acid is.

This is actually a special protein that is found in the human body, but it’s highly concentrated on the skin. It has a very powerful function, which is to ensure the lubrication of your movable parts. This is the reason why it’s highly recommended for those who are suffering from joint pains.

Besides that, it is considered to be the best companion for your collagen. As you grow old, you will start to lose collagen due to overexposure to sunlight or the production of a lot of free radicals. When this happens, your skin would start to lose its suppleness or firmness.

Hyaluronic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）, with its great ability to retain water, can ensure that your skin would not suffer that way—unless you’re really old. It can still hold collagen together and delay the anti-aging process. Hyaluro-nic acid has also been found to be effective in treating wounds or scars.

What are the benefits of hyaluronic acid topical?
One of the greatest benefits of using hyaluronic acid topical is its method of use. Since the product is directly applied into your skin, not taken orally or injected, it becomes a much safer option for those who like to increase hyaluro-nic acid in their body. In fact, for women who are undergoing pregnancy, this is a safe product to use.

It also means that it has the least side effects. For example, injectables can sometimes leave bruising or purple marks on the targeted area, which can unsightly to look at. If you have taken oral hyaluronic acid （Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）that has high molecular weight, your intestine would find it difficult to absorb the protein into the body and make it something useful.

Hyaluro-nic acid topical can also come in different topical skincare products. For instance, you have the topical gel, which is actually a combination of water and hyaluronic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） powder. There are eye creams, skin creams, moisturizers—and a whole lot more. It’s definitely way cheaper than other hyaluronic（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） products that are sold in the market.

Most of all, it can keep your skin moisturized all the time since it will slow down the evaporation of oil from your skin.

What are the downsides?
Nevertheless, there are disadvantages of using topical hyaluro-nic acid products. A lot of scientists and experts would tell you that these topical products are up to no good simply because they are not easily absorbed by the skin, even if it’s mixed with collagen. Their molecules are large enough to do so; therefore, the topical hyaluronic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） can moisturize but not reduce the appearance of wrinkles or topical acne scars.

You can, however, look for those that have lower molecular weights since they prove to be easier to absorb by the skin.

Article Source:

http://www.pure-hyaluronic-acid.com/hyaluronic-acid-topical-6/

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The description of HA (Sodium Hyaluronate Food grade,Sodium Hyaluronate for Food grade,Food grade Sodium Hyaluronate)

1.Discovery of H-A:In 1934, Karl Meyer isolated a formerly unknown glycosaminoglycan from the vitreous humor of the bovine eye. It differed from any of the other previously discovered glycosamlnoglycans in that it did not contain sulffur. With its distinctive structure, its function within the body was unique. It was named hyaluronan(Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate) and further scientific study ensued. At the time of its discovery, the new compound took on two names: hyaluronan when referring to its endogenous synthesis and hyaluro-nic acid when discussing research conducted outside of the body-huma or animal. Today hyaluronan is comonly referred to as hyaluro-nic acid, regardless of the context in which it is spoken.
2.Structure of H-A:Hyaluro-nic Acid is linear, unbranched, high molecular weight polysaccharides containing a repeating disaccharide unit (D-glucuronic acid and N-acetyl glucosamine). H-A, in its natural state, weighs about from 0.5-3.0 million daltons. Its weight lends itself to high viscosity and excellent lubrication within the body. The other glycosaminoglcans in the body include chondroitin sulfate, keratan sulfate, dermatan sulfate, and heparin sulfate.

3. Distribution of H-A:H-A widely consists in the extracelluar spaces of animal tissue. Almost kinds of animal tissue contain the different quantity of H-A. Today Hyaluro-nic Acid （Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） has been found from skin, cockcomb, brain, vitreum, connective tissue, umbilical cord, human serum, articular fluid, gristle, human urine, cock embryo, oocyte, artery and vein etc.
HYALURONIC ACID(Topical Grade)

Itemss	Specifications
Description	White powder
pH	6.0~7.5
Glucuronic Acid	≥43%
Molecular Weight	≥1.00¡Á10⁶
Transparency(in 0.1%aq.sol.,)	≥99.0%
Protein	≤0.1%
Loss on Drying	≤10.0%
Heavy Metals(Pb)	≤20ppm
Arsenic	≤2ppm
Nitrogen	3.0~4.0%
Kinematic Viscosity	≥40mm²/s
Bacteria Count	<10cfu/g
Mold and Yeast	<10cfu/g
Staphylococcus Aureus	Negative
Pseudomonas Aeruginosa	Negative

1%HYALURONIC ACID Solution(Topical Grade)

Items	Specifications
Description	Transparent,colorless
pH	6.0~7.5
Glucuronic Acid	≥4.8mg/ml
HYALURONIC ACID	≥1.0g/100ml
Transparency	≥99.0%
Protein	≤0.001%
Heavy Metals(Pb)	≤0.2¦Ìg/ml
Arsenic	≤0.02¦Ìg/ml
Intrinsic Viscosity	10000~18000mPa¡¤s
Bacteria Count	<10cfu/g
Mold and Yeast	<10cfu/g
Staphylococcus Aureus	Negative

HYALURONIC ACID(Food Grade)

Sodium Hyaluronate Food grade,Sodium Hyaluronate for Food grade,Food grade Sodium Hyaluronate

Items	Specifications
Description	White powder
pH	6.0~7.5
Glucuronic Acid	≥43%
Stake density	0.2~0.4g/cm³
Los on Drying	≤8.0%
Heavy Metals(Pb)	≤20ppm
Arsenic	Measure up to Chinese Pharmacopeia
Powerful Heat Remain	≤13.0%
Bacteria Count	<10cfu/g
Mold and Yeast	<10cfu/g
Staphylococcus Aureus	Negative
Salmonella	Negative
Escherichia Coli	Negative

Article Source:

http://www.nova-bt.com/pages/product_en.html#et1

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Is it Safe to Use Topical Hyaluronic Acid Skin Care Products to Preserve Our Youth Naturally?

How come villagers from Japan looked younger than people in urban areas like New York in United States, based on their facial physical appearance?

Our skin starts to form wrinkles when less amount of extracellular matrix (ECM) in the skin cells to resist compression as it provide swollen force by absorbing a lot of water. Literally, it means an inflated balloon loses its original shape when air leaks out massively from it. Then, it becomes deflated and this symbolizes the condition of the old skin cells.

When ECM is decreasing as we age, how do we replenish the ECM in order to produce an anti-aging effect on the skin?

In order to answer these questions above, the current solution is hyaluro-nic acid(Sodium Hyaluronate Food grade,Sodium Hyaluronate for Food grade,Food grade Sodium Hyaluronate) - which it is the mainly used in anti wrinkle topical skin care products to preserve our fountain of youth.

This particular acid is mainly produced in our body tissues in which comprise epithelial tissues, connective tissues and neural tissues.

Examples of skincare products that have this common acid which has its own distinctive chemical properties:
·Serum - This particular acid binds and attracts water to the skin to maintain softness and suppleness. It boosts skin moisture as it soothes reddened, irritated and sensitive skin.
·Moisturizer/moisturizer toner - This acid has the ability to retain and hold moisture; and it is also a good water binding agent. It has the properties to maintain youthful, healthy and vibrant skin. This toner is meant for dry and oily skin. In this case, you should use a very gentle cleanser and alcohol free toner that has good water binding agent properties.

What is the difference between topical HA skin care products and HA gel-based wrinkle fillers?
HA gel-based wrinkle fillers are injected under a wrinkle, whereas topical (Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate)H-A skin care products does not penetrate skin. It is proven that topical （Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）(Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate)H-A skin care products are safe to consumers in which it is used as a good moisturizing ingredient.

Why opting for HA wrinkle fillers is such a bad idea
It is a bad idea if you opt for (Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate)H-A gel-based wrinkle fillers. If it is injected too superficially, a blue-grey color will be formed because of the melanin found in the dermis - it is also known as "Tyndall effect" dermatosis or Ashy dermatosis.

In fact, candidates who are injected by （Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate）H-A gel-based fillers might have complications at the injection site such as bruising, redness, pain, itching, and swelling when they consume the following drugs and supplements that are listed below:
·Vitamin E supplements
·St. John's Wort
·Aspirin
·Nonsteroidal anti-inflammatory drugs (NSAIDs)

Most people are confused with two types of hyaluro-nic acid anti aging products. In fact, topical hyaluronic skin care products are only safe to use and the other able to cause several complications. Therefore, topical hyaluronic (Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate)is commonly used as a natural anti aging product.

Article Source:

http://EzineArticles.com/?expert=J.J._Yong

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Rooster comb hyaluronate-protein, a non-covalently linked complex

C P Tsiganos, D H Vynios, and D L Kalpaxis

Hyaluronan from rooster comb was isolated by ion-exchange chromatography on DEAE-cellulose from tissue extracts and papain digests. The preparations were labelled with [14C]acetic anhydride and subjected to CsCl-density-gradient centrifugation in 4 M-guanidinium chloride in the presence and absence of 4% ZwittergentTM 3-12. A radioactive protein fraction was separated from the Hyaluronan (Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate) when the zwitterionic detergent was also present. The protein could also be separated from the glycosaminoglycan by chromatography on Sepharose CL-6B eluted with the same solvent mixture. The protein fraction contained three protein bands of Mr 15,000-17,000 as assessed by polyacrylamide-gel electrophoresis in 0.1% SDS, and seemed to lack lysozyme activity. No evidence of other protein or amino acid(s) covalently linked with the Hyaluronan（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） was obtained. The hyaluronate-protein complex may be re-formed upon mixing the components, the extent of its formation depending on the conditions used. The results show that, as in chondrosarcoma [Mason, d'Arville, Kimura & Hascall (1982) Biochem. J. 207, 445-457] and teratocarcinoma cells [Prehm (1983) Biochem. J. 211, 191-198] the rooster comb Hyaluronan also is not linked covalently to a core protein.

Article Source:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1146657/

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Injectable Hyaluronic Acid Derivative Supplementation

Hyaluronic acid(Sodium Hyaluronate Food grade,Sodium Hyaluronate for Food grade,Food grade Sodium Hyaluronate) is a normal part of synovial fluid. Supplemental hyaluro-nic acid is injected into affected joints only once a week, for 3 to 5 weeks, to ease pain symptoms. The benefits may last up to 12 months. Doctors usually give injections only to people who have not had success with other treatments.
How Injectable Hyaluronic Acid Derivative Supplementation Works
Supplements of hyaluro-nic acid help restore the health of the joint by increasing the thickness of the synovial fluid. This lubricates the joint, which can allow a greater range of motion with less pain.
Possible Side Effects of Injectable Hyaluronic Acid Derivative Supplementation
Use of injectable hyaluro-nic acid（Sodium hyaluronate for food grade,Sodium Hyaluronate Food grade,Food grade Sodium Hyaluronate） may cause any of the following side effects.

Article Source:

http://health.discovery.com/centers/articles/articles.html?chrome=c21&article=LC_57&center=p02

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