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Hyaluronic Acid (HA)

Sodium Hyaluronate-Cosmetics grade

Sodium hyaluronate-Food grade

Sodium hyaluronate-Eye drop grade

Sodium hyaluronate-Injection grade

Sodium hyaluronate-Feedstuff grade

 
Hyaluronic Acid Knowledge 

Hyaluronate's Structure
The Latest Craze In "Natural" Skin Care?
 A Breakthrough For A More Youthful Appearance
Nourish Your Skin From the Inside Out with Hyaluronic Acid and Collagen
Hyaluronic Acid Collagen Cream Can Make Your Skin More Youthful
 
 
The Latest Craze In "Natural" Skin Care?
Let's start out by looking at what hyaluronic acid actually is.
Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is a naturally occurring biopolymer, which serves important biological functions in bacteria and higher animals including humans. Naturally occurring, hyaluro-nic acid may be found in the tissue of higher animals, in particular as intercellular space filler. HA(Hyaluronan) is found in greatest concentrations in the vitreous humour of the eye and in the synovial fluid of articular joints, but is also found in the skin, connective tissue and elsewhere in the body.

Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) was made 'famous' by an ABC News report in which Connie Chung visited a Japanese village by the name of Yuzurihara. She found that the people there were living longer, looked younger, and were more flexible and active than their western counterparts. These Japanese villagers, in their 80s and 90s, have smooth wrinkle-less skin, a full head of hair and apparently no need for glasses.

So what is it, that allows these Japanese to be so much more youthful, lead active, productive lives at their advanced age, where as in western countries most people in their 80s and beyond are in old-age homes?

The conclusion drawn in the ABC report was that these people ate 'sticky vegetables' and that this factor was the secret to their apparent youth. In addition, the oestrogen-like molecules in their diet, fermented forms of soy in miso paste and tofu, seem to play an important role. These molecules, along with natural oestrogen, send a signal to the fibroblast cells to make more hyaluro-nic acid. But is this the whole answer? - I don't think so, but I'll get to this a little later.

Next, let's look at what Hyaluronic acid does.
According to scientific research by a variety of Universities and researchers, Hyaluronic acid (Hyaluronan,Sodium Hyaluronate) is used in the human body to cushion and lubricate joints, eyes, the skin, and heart valves (see http://www.ctds.info/hyaluronic_acid.html for an in-depth look at all the different diseases, syndromes and conditions). Some treatments, which involve the use of Hyaluronic acid (Hyaluronan,Sodium Hyaluronate) include: treatment for osteoarthritis and other joint problems, as well as a range of eye disorders, retinal detachment, and some cardiovascular disorders.

However, it is in the anti-aging effect on the skin that we are focusing on in this article and the effect hyaluronic acid (Hyaluronan) seems to have on the skin is at the level of promoting the formation of collagen. These are the fibres that firm the skin. Now, hyaluronidase, an enzyme that breaks down collagen fibres, is produced by free radicals and UV radiation.

These factors breaks down fibres of collagen can cause premature wrinkles and sagging of the skin. Focusing on Hyaluronic acid (Hyaluronan,Sodium Hyaluronate), it would seem reasonable therefore, that reducing the free radicals is a major key to reducing the hyaluronidase enzyme and secondly to promote normal levels of hyaluro-nic acid in the skin.

Plant substances known as bioflavonoids, contained in foods such as grape seed extract, blueberry, cranberry, citrus bioflavonoids and milk thistle, etc., inhibit the production of hyaluronidase, which helps to achieve the first aim of reducing the free radicals. In addition, reducing processed foods from our diet, increasing the level of exercise and living a more balanced life style will help in promoting natural levels of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) in our system, not just in the skin...

When considering injecting hyaluronic acid(Hyaluronan,Sodium Hyaluronate) into the skin to treat fine lines and wrinkles, we are once again loosing sight of the holistic approach to treating our bodies and thus run a serious risk of introducing factors, which may lead to side effects or other health problems. Further, we also run the risk of creating an imbalance in the chemical composition of the skin and who knows what possible problems await us as a result.

Some known side effects of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) injections therapy for aging skin include:
·swelling
·infection
·redness
·tenderness
·acne
·lumps
·tissue hardening
·unknown risks when used in combination with collagen

These side effects are serious enough to reconsider using Hyaluronic Acid injections therapy of hyaluronic acid (Hyaluronan) as an anti-aging treatment for the skin.

Remember too, that the people in the Japanese village do not use Hyaluronic Acid injections therapy(hyaluronic acid injections)... They life an holistic life style incorporating unprocessed foods and physical activity together with a balanced mind-set and life style.

So where can you get a holistic source of hyaluronic acid from?
There are a couple of ways. The first is from "starchy root vegetables" such as the ones mentioned by the village doctor in the ABC report which include: Satsumaimo, a type of sweet potato; Satoimo, a sticky white potato; Konyaku, a gelatinous root vegetable concoction; and Imoji, a potato root.

These vegetables help the cells of the body to thrive and retain moisture. Further, they keep joints lubricated, protect the retina of the eye and keep the skin smooth and elastic by promoting collagen.

Another source of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate), for non-vegetarians, is to eat animal parts known to contain a lot of hyaluro-nic acid. You could make a broth from fish bones. That is, once you've taken off the fillets, boil the rest of the fish, including their head and make a fish stock. Similarly, you can make a meat broth using animal joints, sinews and tendons, then adding a few root and other vegetables to create a healthy, nourishing soup.

In conclusion, at Wildcrafted Herbal Products we do not believe that adding isolated ingredients in elevated concentrations to our natural skin care products is a preferred option. Rather, using a holistically natural approach to skin care and for that matter health care is a far more preferable option.

Skin care is as much about taking care of your skin as it is taking responsibility and care of your overall health and wellbeing. Your skin is not an isolated part of your body and should not be treated as such.

Again I would like to remind you of the Japanese villagers - they do not inject themselves with hyaluro-nic acid, they do not use Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) in isolation, they do however life a healthy, active and mostly balanced life style.

Danny Siegenthaler is a doctor of traditional Chinese medicine and together with his wife Susan, a medical herbalist and Aromatherapist, they have created Natural Skin Care Products by Wildcrafted Herbal Products to share their 40 years of combined expertise with you.

Join our Natural Skin Care Newsletter – it’s fun, free and Informative and you receive a free eBook on natural skin care.
Article Source:
 http://EzineArticles.com/?expert=Danny_Siegenthaler

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A Breakthrough For A More Youthful Appearance
People get wrinkles. It's a fact of life - or is it? Thanks to an amazing scientific discovery, we now realize that we may be able to reduce or delay the appearance of wrinkles!

How do Wrinkles Develop?
The aging of your skin causes a decline in its functionality. The first noticeable change in aging skin is sagging; the skin appears loose and does not "bounce back" as easily when pinched or pulled. Next, fine lines appear, followed by deeper ones as the skin undergoes greater structural changes. These changes are followed by alteration in color and texture. Brown spots appear on the hands and face and the skin becomes thin and dry. Typically, this is what we learn to accept as time goes by - but it doesn't have to be!

Living Wrinkle-Free
As reported by ABC News anchorwoman Connie Chung on Primetime, an amazing substance may contribute to longer-lasting youth. In the village of Yuzuri Hara, Japan, the people there routinely live into their 90ís and longer!

More than 10% of the population of the village is aged 85 or older - 10 times the American average. Not only are the residents of Yuzuri Hara living longer, but they are also quite healthy - they are rarely sick and diseases like cancer, diabetes and Alzheimer's are relatively unheard of. In addition, many of them have also managed to keep their skin from showing signs of aging! This is especially amazing when you consider that residents of the village typically work outdoors (farming) in the sun for years, never once using sun block or skin cream; yet their skin remains remarkably soft, smooth and relatively wrinkle-free.

Dr. Toyosuke Komori, the town doctor believes that the key may be locally grown starches, which may help to stimulate the body's natural creation of a substance called hyaluro-nic acid , which aging bodies typically lose. Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is a key component of collagen and may help to fight the inevitable aging process by improving cellular hydration. Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) also functions as a free radical scavenger and as an antioxidant. These properties may offer protection against skin damage caused by the sun. In fact, Dr. Komori was quoted by ABC Primetime as saying; "I have seen a woman in her 90's with spotless skin."

Hyaluronic Acid - the Miracle Nutrient
The function of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is always about hydration and separation. Hydration because it holds on to water and separation because it acts as a structural component throughout the body.

H-A can be found naturally in every tissue of your body. Nearly 50% of your body's Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is in your skin; there it creates volume, resulting in a healthy and vital appearance. As you age, however, you lose this vital youth-enhancing substance.

H-A is important for more than just skin health. Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) helps to keep your skin moist and your joints lubricated, acting as a buffer to protect your cells. In the United States, Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) has also been used for years in eye surgery as a shock absorber to protect the retina and has been proven effective in lubricating arthritic joints. It acts as a major internal lubricant, playing a crucial role in slowing down cellular mitosis - a crucial aspect of cellular repair - and joint health. Your joints are surrounded by a membrane called the synovial membrane, which forms a capsule around the ends of the bones. This membrane secretes a liquid called the synovial fluid. Current research into osteoarthritis and pain has shown positive results in the treatment of joint pain and cartilage formation with Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate). Patients who have used Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) have experienced a decrease in pain, improved range of motion and improved cellular repair to damaged connective tissues.

H-A is also found in the extracellular matrix (ECM). The ECM is composed of material produced by the cells and excreted to the extracellular space within the tissues. All nutrients and metabolic waste are transported through the ECM. Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is a major constituent of the ECM and serves as an essential structural element of the ECM.

Unfortunately, H-A also has a "half-life" (the amount of time required for half of the molecule to decay) of less than one day in the epidermis (outer skin layer) and is easily eliminated from your cells. It therefore must be continually replenished.

A leading Japanese pharmaceutical company tested Hyaluronic Acid supplements on 1,000 people. Roughly 50% reported smoother skin, less fatigue and better eyesight; but thatís not all. According to Brian Toole, Ph.D., Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) may even have wound healing and tissue-reconstruction applications - it has even been used to help minimize the appearance of bruises and scars!

You can have Beautiful Skin!
The ECM fills up the space between the skin cells. This makes the skin soft, smooth and elastic. As your amount of H-A decreases, the ECM becomes dehydrated, producing dry, rough, wrinkled skin. Itís not unlike the drying of fruit. A plum starts out plump and moist. Remove the water and you get...a prune.

Truly radiant skin comes from within. Your skin's ability to physically glow depends upon its ability to retain and hold moisture within the cells of its dermis (inner layer). In fact, your skin's dermis layer is made up of about 70% water.

The amount of water that you have depends largely on your age and health. According to J. M. Seigneuret, Ph.D., a proper water balance is vital to your skinís condition. Hyperhydration causes the skin to crumple up and swell (that "pruney" look after being submerged in water for a long time) and dehydration promotes the loss of elasticity and wrinkling (the "crocodile" look).

Normally, nothing is more abundant in the human skin cell than Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and water. In fact, according to Aimo Niskanen, D.V.M., Ph.D., H-A can retain up to 1,000 times its own weight in moisture! Dr. Clive Solomons, Ph.D., F.A.I.C., has also noted that H-A acts as a gel to help keep your tissues hydrated.

This is why H-A has become a very popular ingredient in high-quality cosmetics; but topical creams can only bind moisture to the outer surface of your skin! When taken internally, Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) reaches the deep inner layers of the epidermis where topical applications cannot reach.

How could HA Work for You?
H-A may be one of the most important substances in your body. It is a natural component of your skin and plays a major role in maintaining the cellular health of not only your skin, but also your eyes and joints as well.

Throughout your lifetime, your body's cells lose a large part of their essential moisture. Fifty-year-olds are estimated to have less than half the hyaluro-nic acid(Hyaluronan) they had in youth! By replenishing the moisture with the support of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate), you may be able to help reverse the signs typically associated with cellular aging, giving you back that youthful glow!

Columns of fibers, made up mostly of collagen and elastin, provide support from below the surface layers of your skin. This essentially forms a "molecular sponge" known as connective tissue. The spaces within this sponge are filled with a composition of water, protein complexes and HA(Hyaluronan).
The main problem with getting more H-A into your body is that the molecule itself is large and hard to properly absorb. This problem may be solved by breaking down the H-A molecule into a smaller form. This lower weight may become more stable and thus more bioavailable to your body.Hyaluronic Acid(HA,Hyaluronan)injections(supplements),Sodium Hyaluronate
The H-A found in Ultra HA™ is derived from rooster combs. Rooster combs are a very rich source of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and the purest source of H-A available. Clinical trials that have been performed on H-A have used rooster combs as their source, because of its purity.
The weight of H-A derived from rooster combs is 1.2 - 1.5 million daltons. A dalton is an arbitrary unit of measurement used in science. Scientists in Japan have developed a new technique to permit absorption of the molecule. By using an enzyme-cleaving technique, naturally derived H-A is broken down into lower molecular weight polymers. These new smaller molecules weigh 1/10 of their original weight, between 100,000 - 120,000 daltons. This is important, as H-A can only be absorbed as a low molecular weight molecule. Ultra H-A™ with H-A was designed with these smaller, more concentrated Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) molecules to work from the inside out, to help lock in vital moisture to help replenish the natural cartilage cushion between your joints and also promote firmer, smoother skin.

Be Good to Your Skin!
In a recent study, 96 women between the ages of 22-65 took H-A derived from rooster combs for 45 days. Subjective monitoring was conducted and the results were clearly significant. This evidence suggests that low molecular weight H-A may help your body to slough off old, dead skin cells from the outer layer much faster, forcing your body to create new skin cells. This may help to support smoother skin with a more youthful glow; virtually eliminating the need for harsh chemical peels, messy creams or perfumed lotions! Ultra H-A™ contains H-A derived from rooster combs - the same as that effectively used in the study!

Incredible Offer!
Aging and the environment can be so damaging to your body and falling Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) levels as you age can make you look old before your time. Do you want to have smoother, younger-looking skin? When you call 1-800-772-2724 now and order 3 bottles of Ultra H-A™ , you'll receive a fourth bottle Absolutely FREE! Hurry and order Ultra H-A™ today!
Article Source:
http://www.greatamericanproducts.com/pages/Home/Articles/Hyaluronic_Acid:_A_Breakthroug

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Nourish Your Skin From the Inside Out with Hyaluronic Acid and Collagen
Cosmeceuticals—a marriage between cosmetics and pharmaceuticals—is the fastest-growing segment of the natural personal care industry. And it’s no wonder. Because if you’re like most people over 40 you want to avoid or get rid of the crow’s feet around your eyes and the vertical lines above your lips.
One of the newest cosmeceuticals to hit the market is hyaluro-nic acid.

What is hyaluro-nic acid?
Hyaluro-nic acid is a non-sulfated glycosaminoglycan distributed widely throughout the body in the connective, epithelial, and neural tissues. It is one of the chief components of the extracellular matrix and contributes significantly to cell proliferation and migration. The average person has roughly 15 grams of hyaluro-nic acid in their body, one third of which is lost and replaced each day.1

How does it work?
The surface layers of the skin are supported from below by columns of fibers made up mostly of collagen and elastin. This network of fibers forms the molecular sponge known as connective tissue.

Keeping Your Skin Hydrated—Hyaluronic Acid and Collagen
The spaces within this sponge are filled with a composition of water, protein complexes, and hyaluro-nic acid. This jelly-like complex transports essential nutrients from the bloodstream, via the capillaries in your skin. Hyaluro-nic acid attracts and holds water, which is what plumps your skin so that wrinkles and lines are less visible.

With properties like that, it is clear that hyaluro-nic acid is vital to:
Curb premature wrinkling
Increase skin hydration
Keep skin moist and smooth
Boost skin elasticity
Enhance collagen synthesis
Nourish healthy skin cell growth
Promote firm skin tone
Support healthier joints
Searching for beauty in all the wrong places
In 2005, Americans spent more than $12.5 billion on cosmetic procedures that promise to help restore the dewy glow of youth. With baby boomers and more men looking for innovative ways to slow the aging process, it’s estimated that the medical-aesthetic economy—including device sales and doctors’ fees—will soon surpass $20 billion.

The problem is, Botox, chemical peels, and fillers are temporary quick fixes, expensive and not without risk. Botox is delivered in tiny, non-lethal doses of botulinum toxin, which interferes with nerve function for months at a time. In the end, it could very well cause permanent nerve damage. Injected fillers meant to plump up wrinkles and lines can result in infection, bruising, swelling, and pain.

And honestly—if you’ve been trying hard to eat a healthy diet, and supplement it with nutritional Hyaluronic Acid supplements why would you even consider injecting your face with chemicals?

Hyaluro-nic acid is a healthy alternative for fighting the effects of aging … and the good news is that it’s inexpensive, natural, and free of side effects.

“… it’s also important to replenish diminishing stores of hyaluronic acid, because HA is one of the skin’s most important components for hydration and moisture retention.”

Nourish your skin from the inside out
Slathering your skin with topical creams and ointments helps protect against the elements, but the best way to maintain moist, beautiful skin is to nourish it from the inside out. Drinking 8-10 glasses of purified water each day is important, but it’s also important to replenish diminishing stores of hyaluro-nic acid, because Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is one of the skin’s most important components for hydration and moisture retention. And without the proper levels of H-A in the upper layers of the epidermis, your skin appears dull and wrinkled.

Can a hyaluronic acid supplement really help?
According to this theory, it can. We’re all exposed to free radicals through daily exposure to UV rays and environmental pollutants, which inevitably degrades and destroys hyaluro-nic acid. Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) begins to decrease in your early 20s and this accelerates when you hit 40. (In fact, 50 year olds are estimated to have less than half the hyaluro-nic acid of people in their 20s.)4 There is a decrease in the amount of hyaluronic fluid and its synthesis, which in turn leads to a decrease in intra-cellular fluid. This results in skin that is drier and more vulnerable to damage.

The formation and maintenance of collagen, which is also vital to maintaining skin elasticity and tone, is affected. You begin to notice more crow’s feet and wrinkles because your skin loses its elasticity.

Luckily, you can enhance the amount and absorption of H-A by taking an inexpensive, natural nutritional supplement. And the added bonus is that Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) helps support healthy joints!

HA is a member of the family of molecules called glycosaminoglycans, which also includes chondroitin sulfate. It is an excellent lubricant in the body.
Hyaluro-nic acid is produced in the human body and is found in the tissues of all animals.
H-A is also a major ingredient of the synovial fluid that lubricates and cushions joints. Without the appropriate levels of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate), the synovial fluid loses its ability to perform, which leaves the joints unprotected and the cartilage undernourished.
H-A was isolated about sixty years ago from vitreous humor that fills the inner chamber of the eye.
Its name is derived from the Greek word for glass (hyalos), which accurately describes its transparent, glassy appearance.

In skin, H-A, along with water and protein complexes, fills the spaces in connective tissue.
The nature of H-A’s molecular structure makes it ideal for attracting and holding water.

Scientific studies
Although there are numerous studies on the injectable form of H-A into knee joints and facial skin, at this time there are no human trials evaluating the oral benefits of hyaluro-nic acid.

Conclusion
You can spend hundreds—even thousands of dollars each year on topical moisturizers that help soften your skin. But if you want to truly give your skin the moisture it needs to maintain elasticity, strengthen collagen and minimize wrinkles and age spots, it’s a good idea to increase your levels of hyaluro-nic acid. Although it’s not proven, it makes sense that a natural hyaluro-nic acid supplement might help. And if maintaining healthy, beautiful skin is important to you, then it’s definitely worth a try.
Article Source:
http://www.smart-publications.com/anti-aging/hyaluronic_collagen.php

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Hyaluronic Acid Collagen – Why It Matters and How You Can Use It To Your Advantage
Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and collagen is one of the main culprits behind skin aging. The average person has around 15-16 grams of hyaluro-nic acid in their body, and about 30% of this is lost and replaced on a daily basis.

Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) attracts and keeps water in one place. This is what helps your skin look less wrinkled and reduces those deep forehead lines. With that said, it is vital to enhance your skin elasticity, promote healthier skin, better skin tone and increase hydration.

Americans spend billions upon billions of dollars on cosmetic surgery in hopes of looking better, but all these things do not last. They sometimes might damage you permanently and the pain after surgery is not worth it in my opinion.

There are better ways to improve your skin naturally. It will be cheaper and more beneficial for your body. It is a lot more important to accept who you are and improve from there.

Many people who have undergone cosmetic surgery are still not happy after their procedure, that’s why most keep coming back just wanting to improve that one little thing, and then they’re happy. I’m sorry to say this but it just ain’t happening for most people.

As you age your Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and collagen levels decrease and this is one of the main reasons why your skin starts to sag and look older.

So how can you use this information to your advantage? The best way you can do it is to use a good natural skin care product, and it is important to know that you do not just want to go out and look at products that contain these ingredients and say that this is all you need.

The truth is that you body cannot directly absorb something like collagen, which is a protein, therefore you need a skin care product that will promote the production of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and collagen in your body.
Article Source:
http://www.articlesbase.com/skin-care-articles/hyaluronic-acid-collagen-why-it-matters-and-how-you-can-use-it-to-your-advantage-1079500.html

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Hyaluro-nic Acid Collagen Cream Can Make Your Skin More Youthful
A Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) collagen cream may very well be the best anti-aging product you could possibly use to make your skin more youthful and smooth. But getting one that's effective is not as straight-forward as it may sound.

In fact, a very large percentage of hyaluro-nic acid and collagen cream products available are useless because they are designed and developed very poorly. Let me explain what I mean so you can avoid getting one that's ineffective...

First of all, do you know why Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) and collagen protein are so important? In comparison to a brick building, collagen proteins are like the bricks the make of the framework of the building. They provide structure and firmness.

But without some type of filler (mortar), the framework has no chance of staying intact. Hyaluro-nic acid is a substance that cushions collagen protein and fills in all the gaps between them. It's also the skin's primary means of moisture retention, as it can hold up to 1,000 times it's weight in water.

Now back to knowing how to tell the different between a quality Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) collagen cream and a poor one...

If you find skin care products that actually contain these important skin elements as ingredients, then you can be pretty confident that they are not effective. Why? Because in molecular form, they are too large to penetrate through the skin. In fact, they just sit on your skin until you wash them off.

The only kind of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) collagen cream that actually works is one that contains ingredients that encourage collagen production and preserve the amount of hyaluro-nic acid that's in your skin.

Every anti-aging product I use contains two ingredients called CynergyTK(TM) and Phytessence Wakame. CynergyTK(TM) is a breakthrough new ingredient that actually stimulates the production and regrowth of collagen protein in the skin. Phytessence Wakame is a special Japanese ingredient that stops the activity of hyaluronidase, an enzyme that constantly breaks down hyaluro-nic acid.
Article Source:
http://ezinearticles.com/?Hyaluronic-Acid-Collagen-Cream-Can-Make-Your-Skin-More-Youthful&id=2222918

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Hyaluronate's Structure
The chemical structure of Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) was determined in the 1950s in the laboratory of Karl Meyer
Hyaluronan is a polymer of disaccharides, themselves composed of D-glucuronic acid and D-N-acetylglucosamine, linked together via alternating β-1,4 and β-1,3 glycosidic bonds. Hyaluronan can be 25,000 disaccharide repeats in length. Polymers of hyaluronan can range in size from 5,000 to 20,000,000 Da in vivo. The average molecular weight in human synovial fluid is 3−4 million Da, and hyaluronan purified from human umbilical cord is 3,140,000 Da.

Hyaluronic acid (HA,Hyaluronan,Sodium Hyaluronate) is energetically stable in part because of the stereochemistry of its component disaccharides. Bulky groups on each sugar molecule are in sterically favored positions, whereas the smaller hydrogens assume the less-favorable axial positions.
Article Source:
http://en.wikipedia.org/wiki/Hyaluronan

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